MAJIN Links Telomeric DNA to the Nuclear Membrane by Exchanging Telomere Cap
نویسندگان
چکیده
منابع مشابه
MAJIN Links Telomeric DNA to the Nuclear Membrane by Exchanging Telomere Cap
In meiosis, telomeres attach to the inner nuclear membrane (INM) and drive the chromosome movement required for homolog pairing and recombination. Here, we address the question of how telomeres are structurally adapted for the meiotic task. We identify a multi-subunit meiotic telomere-complex, TERB1/2-MAJIN, which takes over telomeric DNA from the shelterin complex in mouse germ cells. TERB1/2-...
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ژورنال
عنوان ژورنال: Cell
سال: 2015
ISSN: 0092-8674
DOI: 10.1016/j.cell.2015.10.030